d'Arienzo 1980.
| Methods | RCT | |
| Participants | 28 IBS patients Unclear setting Diagnostic criteria not defined 39% female |
|
| Interventions | Spasmolytic otilonium tds 20 mg 4 weeks | |
| Outcomes | Symptom score, continuous | |
| Notes | No run‐in | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Unclear risk | Not described |
| Allocation concealment (selection bias) | Unclear risk | Not described |
| Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Double blind, procedures not described |
| Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Not described |
| Selective reporting (reporting bias) | Unclear risk | Not described |
| Other bias | Unclear risk | Not described |