Dubarry 1977.

Methods	RCT
Participants	20 IBS patients Outpatient setting Diagnostic criteria not defined
Interventions	Spasmolytic 6 days pinaverium 50 mg tds
Outcomes	Abdominal pain, dichotomous
Notes	No run‐in
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not described
Allocation concealment (selection bias)	Unclear risk	Not described
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Double‐blind, methods not described
Incomplete outcome data (attrition bias) All outcomes	Low risk	No drop‐outs
Selective reporting (reporting bias)	Low risk	Expected outcomes were reported
Other bias	Low risk	The study appears to be free of other sources of bias