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. 2011 Aug 10;2011(8):CD003460. doi: 10.1002/14651858.CD003460.pub3

Fowlie 1992.

Methods RCT
Participants 49 patients
Gastro intestinal outpatient clinic
Mean age 40 years
65% female
Mean duration of symptoms 3.8 years
Interventions Bulking agent 
 3 months mixed cereal and fruit fibre 4.1 g/day
Outcomes Abdominal pain 
 Global assessment 
 Symptom score
Notes GI Outpatients 
 1 week run‐in
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not described
Allocation concealment (selection bias) Low risk Adequate
Blinding of participants and personnel (performance bias) 
 All outcomes Low risk Double‐blind, identical placebo
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Missing outcome data balanced in numbers across intervention groups with similar reasons for missing data across groups
Selective reporting (reporting bias) Low risk All expected outcomes were reported
Other bias Low risk The study appears to be free of other sources of bias