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. 2011 Aug 10;2011(8):CD003460. doi: 10.1002/14651858.CD003460.pub3

Lucey 1987.

Methods RCT with Cross‐over design
Participants 44 Patients
Gastrointestinal outpatient clinic
Manning criteria
Mean age 32 years
68% female
Mean duration of symptoms 60 months
Interventions Bulking agent 
 3 months wheat bran fibre 13g/day
Outcomes IBS symptom score, continuous
Notes GI Outpatients 
 No run‐in
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not described
Allocation concealment (selection bias) Unclear risk Not described
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Double‐blind, methods not described
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk 16 patients dropped out. Reasons for withdrawal not reported
Selective reporting (reporting bias) Low risk Expected outcomes reported
Other bias Low risk The study appears to be free of other sources of bias