Ritchie 1979.
Methods | RCT | |
Participants | 24 patients Secondary setting Diagnostic criteria not defined Mean age 38 years 77% female |
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Interventions | Bulking agent 4 weeks ispaghula husk, 1 sachet 2 dd Spasmolytics hyoscine 4 dd 10 mg 4 weeks |
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Outcomes | Global assessment, dichotomous | |
Notes | Hospital setting No run‐in | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Not described |
Allocation concealment (selection bias) | Low risk | Centralized randomization by hospital pharmacist |
Blinding of participants and personnel (performance bias) All outcomes | Low risk | Double‐blind, double‐dummy. Dummy preparations were identical to active |
Incomplete outcome data (attrition bias) All outcomes | Low risk | 4 drop‐outs |
Selective reporting (reporting bias) | Low risk | Expected outcomes were reported |
Other bias | Low risk | The study appears to be free of other sources of bias |