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. 2011 Aug 10;2011(8):CD003460. doi: 10.1002/14651858.CD003460.pub3

Ritchie 1979.

Methods RCT
Participants 24 patients
Secondary setting
Diagnostic criteria not defined
Mean age 38 years
77% female
Interventions Bulking agent
4 weeks ispaghula husk, 1 sachet 2 dd 
 Spasmolytics 
 hyoscine 4 dd 10 mg 4 weeks
Outcomes Global assessment, dichotomous
Notes Hospital setting 
 No run‐in
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not described
Allocation concealment (selection bias) Low risk Centralized randomization by hospital pharmacist
Blinding of participants and personnel (performance bias) 
 All outcomes Low risk Double‐blind, double‐dummy. Dummy preparations were identical to active
Incomplete outcome data (attrition bias) 
 All outcomes Low risk 4 drop‐outs
Selective reporting (reporting bias) Low risk Expected outcomes were reported
Other bias Low risk The study appears to be free of other sources of bias