Tabas 2004.

Methods	RCT
Participants	90 patients Voluntary participants through advertisement Rome I criteria Mean age 46 years 74% female
Interventions	Antidepressant paroxetine (SSRI) 10 or 20 mg od for 12 weeks
Outcomes	Abdominal pain, dichotomous Global assessment, dichotomous
Notes	69 of 81 took part in high‐fibre open label trial 7 weeks before
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Computer generated
Allocation concealment (selection bias)	Low risk	Centralized randomization by hospital pharmacist
Blinding of participants and personnel (performance bias) All outcomes	Low risk	Double‐blind, researchers and patients were unaware of assignment until the conclusion of the last visit
Incomplete outcome data (attrition bias) All outcomes	Low risk	Missing outcome data balanced in numbers across intervention groups with similar reasons for missing data across groups
Selective reporting (reporting bias)	Low risk	Expected outcomes were reported
Other bias	Low risk	The study appears to be free of other sources of bias