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. 2021 Dec 23;23(1):141. doi: 10.3390/ijms23010141

Figure 2.

Figure 2

RvD2 counter-regulates histamine-stimulated high molecular weight glycoprotein secretion in cultured conjunctival goblet cells derived from both rats and humans. CGCs derived from rat (a) and human (b) were incubated with increasing concentrations of RvD2 (10−9–10−7 M) for 30 min before stimulation with histamine 10−5 M and glycoprotein secretion was measured. The average fold increase above basal was calculated and shown in (a) for rat-derived and (b) for human-derived cells. Data are mean ± SEM from 3 rats and 3 humans. * Indicates a significant difference from basal. # Indicates a significant difference from stimulus alone.