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. 2021 Dec 24;23(1):195. doi: 10.3390/ijms23010195

Figure 2.

Figure 2

Effect of anti-diabetics on systemic glucose homeostasis and dyslipidemia in iNOS-/- mice. Systemic glucose and lipid homeostasis in iNOS-/- mice after treatment with metformin or pioglitazone. (A) Intraperitoneal glucose tolerance test (GTT) with AUC calculated from IPGTT data, (B) Fasting blood glucose levels, (C) Relative liver-body weight ratio and (D) Serum lipids and total nitrite levels. Data are represented as mean ± SD (n = 7–12). * p < 0.05, ** p < 0.01 and **** p < 0.0001 between indicated groups. # p < 0.05, ## p < 0.01, ### p < 0.001 and #### p < 0.0001 vs. iNOS-/- in GTT curve.