Table 1.

Roles of miR408 and its targets in abiotic and biotic stress in plants.

Stresses	Species	miRNA	Target Genes	References
ABIOTIC
Mild drought	Prunus persica	miR408	Plastocyanin,	[68]
			Copper ion
			binding protein
	Prunus dulcis	miR408	No
Severe drought	Prunus persica	miR408	Plantacyanin
	Prunus dulcis	miR408	No
	Interspecific Prunus persica–Armeniaca Prunus dulcis	miR408	No
Drought	Convolvulacee	miR408	No	[69]
	(tolerant wild Ipomoea
	campanulata)
	Convolvulacee	miR408	No
	(sensitive Cultivated
	Jacquemontia Pentantha)
	Convolvulacee	miR408	No	[70]
	(tolerant wild Ipomoea
	campanulata )
	Convolvulacee	miR408	No
	(sensitive Cultivated
	Jacquemontia Pentantha )
	Oryza sativa	miR408-3p	Plantacyanin,	[39,71]
	(tolerant Cultivars N22, dana)		plastocyanin-like
			domain,
			containing
			proteins
	Oryza sativa	miR408-3p	No
	(sensitive cultivars PB1, IR64)
	Triticum aestivum	miR408	No	[72]
		(root)
		miR408	No
		(leaf)
	Lycopersicon esculentum	miR408a-3p	No	[73]
	(sensitive)
	L.esculentum var.	miR408	No
	Cerasiforme (tolerant)
	Pisum sativum	miR408	No	[72]
	Oryza sativa	miR408	plastocyanin genes (Os01g53880 and Os09g29390)	[74]
	Arabidopsis thaliana	miR408	Cupredoxin	[22]
			Plantacyanin
			LAC3
	Cicer arietinum	miR408	No	[75]
Water	Ipomoea campanulate	miR408	Plantacyanin	[70]
deficit	(tolerate)
	Jacquemontia Pentantha	miR408
	(sensitive)
	Pisum sativum	miR408	P1B-ATPase	[76]
	Medicago truncatula	miR408	Plantacyanin	[42]
Dehydration	Hordeum vulgare	miR408	Plantacyanin	[77]
Salinity	Oryza sativa	miR408	DSHCT	[40]
			Plastocyanin-like
	Salvia miltiorrhiza	miR408	No	[78]
	Arabidopsis thaliana	miR408	Cupredoxin	[22]
			Plantacyanin
			Uclacyanin
			LAC3
Cold		miR408	Cupredoxin
			Plantacyanin
			Uclacyanin
			LAC3
Osmotic		miR408	Cupredoxin
			Plantacyanin
			Uclacyanin
			LAC3
Oxidative		miR408	Cupredoxin
			Plantacyanin
			Uclacyanin
			LAC3
Low dose	Oryza sativa	miR408	DSHCT	[27]
rate γ-ray
High dose		miR408
rate γ-ray
Nutrient deprivation
	Zea mays	miR408	Cupredoxin	[79,80]
Nitrogen			SOD1A
deficiency	Arabidopsis thaliana	miR408	Laccase	[81]
			Plantacyanin
Carbon, nitrogen,		miR408	LAC3	[28]
and sulfur			LAC13
deficiency
Copper deficiency		miR408	LAC3	[22,36]
			LAC12
			LAC13
			Plantacyanin
Iron deficiency		miR408	LAC3	[18]
			LAC12
			LAC13
			Plantacyanin
Boron deficiency		miR408	Plantacyanin	[82]
			LAC3
			LAC13
			Cu/Zn SODs
			(CSDs)
Excess fertilizer	Linum usitatissimum	miR408	No	[83]
Phosphorus deficiency	Arabidopsis thaliana	miR408	No	[84]
	Glycine max	miR408	No	[85]
	Triticum aestivum	miR408	No	[86]
Zinc deficiency	Sorghum bicolor	miR408	Plantacyanin	[87]
Potassium	Triticum aestivum	miR408	No	[88]
deficiency
Heavy metals
Cadmium	Triticum aestivum	miR408 (12h, leaves)	Chemocyanin-like protein	[89]
		miR408 (24h, leaves)
		miR408 (6, 12, 24 and 48h, roots)
	Oryza sativa	miR408	bZIP, ERF,	[29]
			MYB, SnRK1
			and HSPs
Arsenate and	Oryza sativa	miR408	No	[30]
arsenite
Manganese	Phaseolus vulgaris	miR408	No	[90]
BIOTIC	Triticum aestivum	miR408	Plantacyanin	[91]
Puccinia graminis
f.sp. tritici
Rhizoctonia solani	Oryza sativa	miR408	No	[92]
Lipopolysaccharide	Arabidopsis thaliana	miR408	Plantacyanin	[31]

Green: increased miR408 abundance; red: decreased miR408 abundance. DSHCT, DOB1/SK12/helY-like DEAD-box Helicase; LAC, laccase.