Figure 2.

Survival and body weight dynamics in rats after lithium–pilocarpine induced status epilepticus (SE). (a) The Kaplan–Meier survival curves show no effect of MTEP treatment on survival (Gehan–Breslow–Wilcoxon test ꭓ² = 1.3, p = 0.72). (b) Bodyweight dynamics are presented as alterations in weight relative to the average weight before SE. Only the rats that survived during the latent phase were used for bodyweight dynamics analysis (Pilo: n = 10; MTEP: n = 14). The data are presented as mean values with standard errors of the mean. Mixed ANOVA analysis showed no MTEP influence on weight dynamics (Greenhouse–Geisser F₂._2,53.₉ = 0.5, p = 0.7, η_p² = 0.02). (c) Spontaneous recurrent seizure (SRS) characteristics. The percentages of rats with SRS in the Pilo and MTEP groups do not differ; data includes video-recorded seizures and attacks noted during behavioral testing (left panel). The average duration of video recorded SRS (middle panel) and total SRS time (right panel) are not affected by MTEP treatment (student’s t-test, p > 0.05 for both parameters). The bars represent mean values, the error bars represent standard errors of the mean, and the circles represent the individual values of each animal.