Table 1.

Phenotypes of CIDP [6].

Typical CIDP

CIDP Variants

All the following: Progressive or relapsing, symmetric, proximal and distal muscle weakness of upper and lower limbs, and sensory involvement of at least two limbs Developing over at least 8 weeks Absent or reduced tendon reflexes in all limbs

One of the following, but otherwise as in typical CIDP (tendon reflexes may be normal in unaffected limbs): Distal CIDP: distal sensory loss and muscle weakness predominantly in lower limbs Multifocal CIDP: sensory loss and muscle weakness in a multifocal pattern, usually asymmetric, upper limb predominant, in more than one limb Focal CIDP: sensory loss and muscle weakness in only one limb Motor CIDP: motor symptoms and signs without sensory involvement Sensory CIDP: sensory symptoms and signs without motor involvement

Abbreviation: CIDP, chronic inflammatory demyelinating polyradiculoneuropathy.