Table 1.
Characteristics of the patients.
| Characteristic | Short-Term Storage Group (n = 194) | Long-Term Storage Group (n = 89) | p-Value |
|---|---|---|---|
| Age (years) | 55.50 (42.25, 66.00) | 57.00 (47.00, 69.00) | 0.248 |
| Male sex, n (%) | 120 (61.9) | 56 (62.9) | 0.968 |
| Body mass index (kg/cm) | 27.78 (24.39, 32.65) | 26.73 (23.67, 31.37) | 0.212 |
| Charlson comorbidity index | 3.00 (1.00, 5.00) | 3.00 (1.00, 6.00) | 0.430 |
| Chronic kidney disease, n (%) | 19 (9.8) | 16 (18.0) | 0.081 |
| Immunocompromised, n (%) | 44 (22.7) | 22 (24.7) | 0.822 |
| SOFA at ARDS onset | 11.00 (8.25, 14.00) | 12.00 (8.00, 14.00) | 0.669 |
| SAPS II at ARDS onset | 50.00 (38.00, 64.00) | 55.00 (38.00, 70.00) | 0.320 |
| RASS at ARDS onset | −5.00 (−5.00, −4.00) | −5.00 (−5.00, −4.00) | 0.719 |
| Chronic lung disease, n (%) | 39 (20.1) | 24 (27.0) | 0.256 |
| Mechanical ventilation before admission (days) | 1.00 (0.00, 4.00) | 1.00 (0.00, 4.00) | 0.523 |
| ARDS severity, n (%) | 0.618 | ||
| Mild | 10 (5.2) | 7 (7.9) | |
| Moderate | 47 (24.2) | 19 (21.3) | |
| Severe | 137 (70.6) | 63 (70.8) | |
| ARDS etiology, n (%) | 0.495 | ||
| Pneumonia | 102 (52.6) | 51 (57.3) | |
| Aspiration | 44 (22.7) | 17 (19.1) | |
| Sepsis | 15 (7.7) | 11 (12.4) | |
| Pancreatitis | 6 (3.1) | 2 (2.2) | |
| Other | 27 (13.9) | 8 (9.0) | |
| Ventilation parameters after initial optimization | |||
| PaO2:FiO2 (mmHg) | 157.37 (109.17, 214.44) | 164.47 (111.25, 228.05) | 0.401 |
| Oxygenation index | 15.19 (9.56, 22.57) | 14.35 (8.88, 21.36) | 0.244 |
| PEEP (cm H2O) | 16.60 (14.00, 20.00) | 16.00 (13.25, 18.02) | 0.075 |
| Driving pressure (cm H2O) | 15.52 (13.00, 18.00) | 15.29 (11.85, 18.84) | 0.771 |
| Tidal volume (mL/kg PBW) | 6.86 (5.74, 7.76) | 6.07 (5.48, 7.05) | 0.016 |
| Respiratory rate (breaths/min) | 20.00 (18.00, 24.00) | 21.00 (20.00, 25.00) | 0.306 |
| Compliance (mL/cm H2O) | 36.40 (27.45, 47.15) | 33.85 (26.98, 49.30) | 0.735 |
| Rescue therapy | |||
| Inhaled nitric oxide, n (%) | 131 (67.5) | 57 (64.0) | 0.660 |
| Prone positioning, n (%) | 132 (68.0) | 52 (58.4) | 0.150 |
| Septic shock, n (%) | 83 (43.2) | 37 (42.5) | 0.999 |
| Lactate (mg/dL) | 16.00 (10.00, 30.00) | 16.00 (10.00, 31.00) | 0.742 |
| RRT, n (%) | 120 (61.9) | 50 (56.2) | 0.439 |
Definition of abbreviations: SOFA = Sequential Organ Failure Assessment, SAPS = Simplified Acute Physiology Score, RASS = Richmond Agitation-Sedation Scale, PEEP = Positive End-Expiratory Pressure, RRT = Renal replacement therapy. Data are expressed as median (25%, 75% quartiles) or frequencies (%), as appropriate.