Table 3.
Comparison of surgical conditions, blood transfusion, and prognosis of patients receiving and not receiving TXA for coagulopathy.
| Variables | All Patients (n = 46) |
Receiving TXA (n = 12) |
Not Receiving TXA (n = 34) |
p Value |
|---|---|---|---|---|
| Median GCS (IQR) | 5.5 (4–9) | 7.5 (5–10) | 5 (4–9) | 0.186 |
| DC (%) | 23 (50.0) | 7 (58.3) | 16 (47.1) | 0.502 |
| Mean operative blood loss (SD) | 649 (499) | 733 (481) | 619 (509) | 0.217 |
| Mean duration of surgery (SD) | 167 (98) | 162 (68) | 168 (108) | 0.910 |
| Blood transfusion (%) | 36 (78.3) | 12 (100.0) | 24 (70.6) | 0.086 |
| Mean blood transfusion volume (SD) | 1053 (1016) | 1438 (1235) | 917 (909) | 0.170 |
| Mean ICU LOS (SD) | 5.9 (6.1) | 6.5 (4.5) | 5.7 (6.7) | 0.187 |
| Median GOS (IQR) | 3 (1–5) | 4 (1–5) | 3 (1–4) | 0.639 |
| Mortality (%) | 17 (37.0) | 4 (33.3) | 13 (38.2) | 0.765 |
Abbreviations: TXA, tranexamic acid; GCS, Glasgow Coma Scale; DC, decompressive craniectomy; ICU, Intensive Care Unit; LOS, Length of stay; GOS, Glasgow outcome scale; SD, standard deviations; IQR, interquartile range.