Table 2.

Differences in intraocular pressure and antiglaucoma medications.

		BL	7 Days	15 Days	1 Month	3 Months	6 Months	12 Months
All eyes	Eyes, n	80	80	79	77	70	68	66
	Mean IOP, mmHg ± SD	22.5 ± 5.3	17.8 ± 7.5	20.5 ± 8.4	17.8 ± 5.5	15.6 ± 4.0	15.3 ± 4.6	15.0 ± 3.6
	Mean IOP reduction from BL, mmHg (%)		4.7 (18%)	1.8 (5.3%)	4.5 (16.6%)	6.5 (26.9%)	6.8 (28.4%)	6.9 (29.0%)
	p-Value		(p < 0.001)	(p = 0.035)	p < 0.001	p < 0.001	p < 0.001	p < 0.001
	Mean MEDs, n ± SD	3.2 ± 1.0	0.7 ± 1.2	0.9 ± 1.3	1.3 ± 1.4	1.6 ± 1.4	1.7 ± 1.4	1.9 ± 1.4
	Mean MEDs reduction from BL, n (p-Value)		2.5 (p < 0.001)	2.2 (p < 0.001)	1.8 (p < 0.001)	1.6 (p < 0.001)	1.5 (p < 0.001)	1.2 (p < 0.001)
Group 1	Eyes, n	50	50	49	47	43	42	40
	Mean IOP, mmHg ± SD	23.0 ± 5.7	17.8 ± 7.9	21.1 ± 9.5	18.6 ± 6.0	16.4 ± 4.4	15.8 ± 5.1	15.6 ± 3.6
	Mean IOP reduction from BL, mmHg (%)		5.2 (20.3%)	1.6 (4.6%)	4.2 (15.1%)	5.9 (23.8%)	6.5 (27.0%)	6.5 (26.8%)
	p-Value		p < 0.001	p = 0.12	p < 0.001	p < 0.001	p < 0.001	p < 0.001
	Mean MEDs, n ± SD	3.0 ± 1.1	0.7 ± 1.2	0.9 ± 1.2	1.3 ± 1.4	1.6 ± 1.4	1.7 ± 1.4	2.0 ± 1.4
	Mean MEDs reduction from BL, n (p-Value)		2.3 (p < 0.001)	2.1 (p < 0.001)	1.7 (p < 0.001)	1.4 (p < 0.001)	1.2 (p < 0.001)	1.0 (p < 0.001)
Group 2	Eyes, n	30	30	30	30	27	26	26
	Mean IOP, mmHg ± SD	21.5 ± 4.7	17.6 ± 7.1	19.4 ± 6.3	16.6 ± 4.5	14.4 ± 2.9	14.5 ± 3.7	14.1 ± 3.3
	Mean IOP reduction from BL, mmHg (%)		3.9 (14.3%)	2.1 (6.2%)	4.9 (19.1%)	7.4 (30.7%)	7.2 (30.3%)	7.6 (32.4%)
	p-Value		p = 0.007	p < 0.069	p < 0.001	p < 0.001	p < 0.001	p < 0.001
	Mean MEDs, n ± SD	3.4 ± 0.8	0.7 ± 1.1	1.0 ± 1.4	1.3 ± 1.3	1.6 ± 1.4	1.7 ± 1.3	1.9 ± 1.4
	Mean MEDs reduction from BL, n (p-Value)		2.8 (p < 0.001)	2.5 (p < 0.001)	2.1 (p < 0.001)	1.9 (p < 0.001)	1.8 (p < 0.001)	1.6 (p < 0.001)

IOP = intraocular pressure; SD = standard deviation; BL = baseline; MEDs = medications.