Table 4.
Microbiota (log cfu/g feces) in patients with prediabetes of the PLC and MO groups during the intervention.
0 wk | 6 wk | 12 wk | p # | Rate of Change 0–12 wk (p Φ) |
||
---|---|---|---|---|---|---|
Blautia coccoides- Eubacterium rectale | PLC | 11.56 ± 0.29 | 11.61 ± 0.45 | 11.75 ± 0.29 | 0.218 | 1.7 ± 3.3 |
MO | 11.63 ± 0.32 | 11.72 ± 0.39 | 11.70 ± 0.38 | 0.7 ± 3.6 | ||
NS | ||||||
Bacteroides fragilis group. | PLC | 9.38 ± 0.80 | 9.39 ± 0.84 | 9.42 ± 0.67 | 0.482 | 0.6 ± 5.5 |
MO | 9.59 ± 0.49 | 9.61 ± 0.57 | 9.58 ± 0.58 | −0.1 ± 4.5 | ||
NS | ||||||
Clostridium cluster IV | PLC | 8.39 ± 0.36 | 8.38 ± 0.58 | 8.49 ± 0.36 | 0.613 | 1.2 ± 5.2 |
MO | 8.43 ± 0.33 | 8.47 ± 0.33 | 8.47 ± 0.39 | 0.5 ± 4.8 | ||
NS | ||||||
Bifidobacterium spp. | PLC | 7.76 ± 0.40 | 7.85 ± 0.47 | 7.90 ± 0.39 | 0.697 | 1.9 ± 4.8 |
MO | 7.78 ± 0.39 | 7.85 ± 0.40 | 7.83 ± 0.41 | 0.9 ± 5.8 | ||
NS | ||||||
Enterobacteriaceae | PLC | 6.59 ± 1.15 | 6.56 ± 0.96 | 6.64 ± 1.02 | 0.404 | 3.5 ± 22.5 |
MO | 6.18 ± 0.86 | 6.42 ± 1.07 | 6.57 ± 0.90 | 7.7 ± 17.5 | ||
NS | ||||||
Enterococcus spp. | PLC | 4.74 ± 1.02 | 5.14 ± 1.09 | 5.04 ± 1.0 | 0.016 | 9.1 ± 23.1 |
MO | 4.89 ± 0.97 | 4.62 ± 0.80 | 4.87 ± 0.78 | 2.5 ± 21.9 | ||
NS | ||||||
Lactobacillus group | PLC | 4.34 ± 1.15 | 4.49 ± 1.06 | 4.67 ± 0.99 | 0.091 | 11.8 ± 26.9 |
MO | 4.37 ± 0.80 | 4.05 ± 0.74 | 4.33 ± 0.70 | 1.0 ± 18.6 | ||
NS | ||||||
Faecalibacterium prausnitzii | PLC | 9.33 ± 0.36 | 9.38 ± 0.39 | 9.46 ± 0.35 | 0.438 | 1.5 ± 4.4 |
MO | 9.42 ± 0.30 | 9.49 ± 0.35 | 9.46 ± 0.38 | 0.5 ± 4.0 | ||
NS | ||||||
Akkermansia muciniphila | PLC | 7.34 ± 1.25 | 6.99 ± 1.58 | 7.18 ± 1.43 | 0.885 | −1.3 ± 16.7 |
MO | 7.19 ± 1.26 | 6.69 ± 1.33 | 6.96 ± 1.56 | −0.5 ± 27.0 | ||
NS |
Between-group differences were assessed with a GLM with within-subject factor “visit”, the fixed factor “treatment” and the interaction “treatment × visit”. The p #-value corresponds to the “treatment × visit” factor. p Φ, Comparison between treatment groups by independent sample T test. NS, not significant.