Table 6.
Biochemical parameters of nerve growth and inflammation in each group and by visit.
| RB | C | RB + C | Total | p-Value ** | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Baseline | 12 w | p-Value * | Baseline | 12 w | p-Value * | Baseline | 12 w | p-Value * | Baseline | 12 w | p-Value * | ||
| BDNF (pg/mL) | 0.77 ± 0.37 a | 0.66 ± 0.34 | 0.384 | 0.58 ± 0.16 ab | 0.56 ± 0.19 | 0.33 | 0.54 ± 0.24 b | 0.64 ± 0.31 | 0.301 | 0.63 ± 0.28 | 0.62 ± 0.28 | 0.888 | 0.036 |
| NGF-R (pg/mL) | 80.23 ± 63.37 | 97.59 ± 104.19 | 0.618 | 63.81 ± 35.49 | 77.5 ± 61.44 | 0.46 | 80.91 ± 66.84 | 83.03 ± 64.27 | 0.872 | 74.98 ± 56.25 | 86.04 ± 77.74 | 0.399 | 0.651 |
| IL-6 (pg/mL) | 0.7 ± 0.42 | 0.95 ± 0.35 | 0.195 | 0.35 ± 0.28 | 0.85 ± 0.35 | <0.001 | 0.52 ± 0.4 | 1.41 ± 1.11 | 0.036 | 0.51 ± 0.37 | 1.08 ± 0.71 | 0.001 | 0.374 |
* Significance within groups, ** significance between groups; data expressed as mean ± standard deviation (SD); significant difference at p-value < 0.05; different letters indicate statistically significant differences between groups; BDNF: Brain-derived neurotrophic factor; NGF-R: Nerve growth factor receptor.