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. 2021 Dec 31;27(1):255. doi: 10.3390/molecules27010255
IASP International Association for the Study of Pain
CNS Central nervous system
PNS Peripheral nervous system
HIV Human immunodeficiency virus
COVID-19 Coronavirus disease 2019
SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2
GRADE Grading of Recommendations Assessment, Development, and Evaluation
NeuPSIG Special Interest Group on Neuropathic Pain
LNP Localized neuropathic pain
PWT Paw withdrawal threshold
PWL Paw withdrawal latencies
CCI Chronic constriction injury
SNL Spinal nerve ligation
TWL Tail withdrawal latencies
STZ streptozotocin
H&E staining Hematoxylin-eosin staining
Cmax Mean peak concentration
Tmax Mean peak time
T1/2 Half-life
NLRP3 NOD-like receptor protein 3
MCC950 A selective inhibitor of the NLRP3 inflammasome
ZDF Zucker diabetic fatty
T2DM Type 2 diabetes mellitus
HPLC-MS High Performance Liquid Chromatography-Mass Spectrometry
ROS Reactive oxygen species
MIA Monoiodoacetate
AUC Area under curve
PTX Paclitaxel
TNF-α Tumor Necrosis Factor-Alpha
IL-1β Interleukin-1β
IL-6 Interleukin-6
IL-10 Interleukin-10
UHPLC-MS ultra-high-performance liquid chromatography tandem mass spectrometry
MMPs Matrix metalloproteinases
T-AOC Total antioxidant capacity
CAT Catalase
T-SOD Total superoxide dismutase
MAD Malondialdehyde
NF-κB Nuclear factor kappa B
Keap1 Kelch-like ECH associated protein 1
Nrf2 Nuclear factor erythroid 2-related factor 2
ATP Adenosine triphosphate
P2X7R P2X receptor 7
TRPA1 Transient receptor potential ankyrin 1
TRP Transient receptor potential
HPS High-throughput screening
GPCR G-protein-coupled receptor
GRP160 G-protein-coupled receptor 160
GPR34 G-protein-coupled receptor 34
GPR40 G-protein-coupled receptor 40
GLP-1R Glucagon-like peptide-1 receptor
CTAP μ-Opioid receptor antagonist
POMC β-Endorphin precursor proopiomelanocortin
C3G Cyanidin-3-o-glucoside
RNS Reactive nitrogen species
TRPM2 Transient receptor potential melastatin 2
TRPM3 Transient receptor potential melastatin 3
TRPM4 Transient receptor potential melastatin 4
TRPC3 Transient receptor potential channel canonical 3
TRPC4 Transient receptor potential channel canonical 4
TRPV1 Transient receptor potential vanilloid type 1
TRPV4 Transient receptor potential vanilloid type 4
RCS Reactive carbonyl species
SP Substance P
CGRP Calcitonin gene-related peptide