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. 2021 Dec 29;27(1):188. doi: 10.3390/molecules27010188

Table 3.

Daily intake of OTA and 2′R-OTA with coffee and cocoa (based on concentrations found in this study and data on consumption in Poland, Hungary and Netherlands).

Country Assumed Values Coffee
Concentration of OTA (µg/kg) Concentration of OTA + 2′R-OTA (µg/kg) *PDI for
OTA
(ng/kg b.w./day)
*PDI for OTA + 2′R-OTA (ng/kg b.w./day) % TDI for OTA % TDI for OTA + 2′R-OTA
Poland Minimum 0.15 0.30 0.02 0.04 0.4 0.7
Median 0.66 0.81 0.08 0.09 1.6 1.9
Maximum 5.15 7.27 0.60 0.85 12.1 17.0
Hungary Minimum 0.15 0.30 0.02 0.04 0.4 0.7
Median 0.66 0.81 0.08 0.10 1.6 2.0
Maximum 5.15 7.27 0.60 0.88 13.0 17.7
Netherlands Minimum 0.15 0.30 0.05 0.10 1.0 2.0
Median 0.7 0.81 0.22 0.27 4.3 5.3
Maximum 5.15 7.27 1.69 2.39 33.8 47.8
Cocoa
Poland Minimum 0.48 0.63 0.00 0.00 0.1 0.1
Median 0.83 0.98 0.00 0.00 0.1 0.1
Maximum 1.96 2.11 0.01 0.01 0.2 0.2
Hungary Minimum 0.48 0.63 0.02 0.02 0.3 0.5
Median 0.83 0.98 0.03 0.04 0.6 0.7
Maximum 1.96 2.11 0.07 0.08 1.4 1.5
Netherlands Minimum 0.48 0.63 0.02 0.02 0.4 0.5
Median 0.83 0.98 0.03 0.04 0.6 0.7
Maximum 1.96 2.11 0.07 0.08 1.5 1.6

*PDI, probable daily intake; TDI, total daily intake; *PDI = C × Cd/b.w., where: C is the concentration of OTA or OTA + 2′R-OTA in coffee/cocoa; Cd is the average daily consumption of coffee/cocoa in the given country, and b.w. is the mean body weight (70 kg). If the measurement for any analyte was below the LOQ, the value LOQ/2 was taken in calculations.