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. 2021 Dec 25;14(1):79. doi: 10.3390/nu14010079

Figure 2.

Figure 2

Possible anti-cancer mechanism of thymoquinone (TQ). TQ caused apoptosis in TNBC cells by inducing apoptotic genes, downregulating anti-apoptotic genes, and generating reactive oxygen species (ROS). TQ also suppresses Akt activation, deactivates Nf-kB, and increases antioxidant enzymes, inhibiting TNBC carcinogenesis.