Table 4.
Observations | 30 min | 2 h | 4 h | 24 h | 48 h | 72 h | 7 Days | 14 Days | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
C | V | M | C | V | M | C | V | M | C | V | M | C | V | M | C | V | M | C | V | M | C | V | M | |
Skin irritation | N | N | 2 × 1n | N | N | 1 × 2n | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
Piloerection | N | N | 2 × 1n | N | N | 1 × 2n | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
Eyes | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
Mucous membranes | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
Irritation | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
Brething | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
Tremors | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
Convulsions | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
Salivation | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
Diarrhea | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
Lethargy | N | N | 1 × 2n | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
Sleep | N | N | N | N | N | N | N | N | 2 × 1n | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
Coma | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
Mortality | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
C = Control; V = Vehicle; M = Methanolic extract of Mangifera indica; N = Normal; 1 × 2n = 1 affected, 2 normal; 2 × 1n = 2 affected, 1 normal.