Skip to main content
. 2021 Dec 27;27(1):146. doi: 10.3390/molecules27010146

Table 5.

Applications of gold nanoparticles (AuNPs) in drug delivery for cancer therapy. Reproduced with permission from reference [88].

Types of Nanoparticles Drug Outcomes
Folate-AuNP # Cyclophosphamide αHFR-positive # breast cancer cells were more sensitive to cyclophosphamide therapy.
MTX-AuNP # Methotrexate Compared to free MTX, the MTX-AuNP have depicted higher cytotoxicity and tumour cell accumulation, as well as improved tumour inhibition.
VCR-AuNP # Vincristine (VCR) Higher cytotoxicity and tumour cell accumulation compared to free VCR.
6MP-AuNP # 6-mercaptopurine Compared to 6MP alone, the 6MP-AuNP have greater antiproliferative effect.
5-FU-Glutathione-AuNP # 5-Flourouracil Compared to free 5-FU, the 5-FU-Glutathione-AuNP have greater anticancer effect.

# Folate-AuNP—Folate-gold nanoparticles, MTX-AuNP—Methotrexate-gold nanoparticles, VCR-AuNP—Vincristine-gold nanoparticles, 6MP-AuNP—6-Mercaptopurine-gold nanoparticles, 5-FU-Glutathione-AuNP—5-Flourouracil-gold nanoparticles, αHFR—Alpha human folate receptor.