Figure 5.

Effect of SPEAF on hydroxyproline content (A) and Col1A1 expression (B) in acetic acid-induced tongue ulcer in rats. Data are presented as Mean ± SD (n = 6). Statistical analysis was performed by one-way ANOVA followed by Tukey’s test. ^a Significant difference from negative control group at p < 0.05. ^b Significant difference from acetic acid group at p < 0.05. ^c Significant difference from ulcer + vehicle group at p < 0.05. ^d Significant difference from ulcer + SPEAF group at p < 0.05. SPEAF: S. persica ethyl acetate fraction.