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Crucial miRNAs involved in osteosarcoma development and progression. Carcinogenesis (a), cell proliferation (b), and cell invasion and migration (c) have been identified as the most illustrative biological implications for miRNAs in osteosarcoma disease. Some of these miRNAs exhibit more than one role in the main stages of osteosarcoma pathology. Furthermore, these regulatory molecules enclose a remarkable potential as biomarkers for osteosarcoma.
