Table 1.
Liver biochemical of COVID-19 patients at admission or during hospitalization.
| References | Countries and regions | Sample size (n) | Abnormal liver biochemical indicators No. (%) | ||||||
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| ALT | AST | GTT | ALP | LDH | ALB | TBIL | |||
| Zhou et al.12 | Wuhan, China | 191 | 59 (31%) | NA | NA | NA | 123 (67%) | NA | NA |
| Zhang et al.59 | Wuhan, China | 82 | 22 (30.6%) | 44 (61.1%) | NA | NA | 68 (93.2%) | 56 (77.8%) | 22 (30.6%) |
| Cai et al.2 | Shenzhen, China | 417 | 54 (14.9%) | 76(18.2%) | 68 (16.3%) | 16(4.8%) | NA | NA | 96 (23.1%) |
| Chen et al.67 | Wuhan, China | 99 | 28 (28.3%) | 35 (35.4%) | NA | NA | 75 (76%) | 97 (98%) | 18 (18.2%) |
| Wang et al.51 | Beijing. China | 105 | 17 (16.2%) | 9 (18%) | NA | NA | NA | NA | 2(4%) |
| Chen et al.68 | Wuhan, China | 274 | 60 (22%) | 84 (31%) | NA | NA | 116 (42%) | 96 (35%) | NA |
| Zhao et al.69 | Jingzhou, China | 91 | 10 (11.0%) | 18 (19.8%) | NA | NA | NA | NA | NA |
| Yang et al.70 | Wenzhou, China | 149 | 18 (12.1%) | 27 (18.1%) | NA | NA | 45 (30.2%) | 9 (6%) | 4 (2.7%) |
| Zheng et al.71 | Changsha, China | 161 | 13 (8.1%) | 22 (13.7%) | NA | NA | 38 (23.6%) | NA | 9 (5.6%) |
| Zhang et al.58 | Wuhan, China | 115 | 11 (9.6%) | 17 (14.8%) | 15 (13%) | 6 (5.2%) | 23% | 63 (54.78%) | 8 (7.0%) |
| Pan et al.18 | Hubei, China | 204 | 27 (13.2%) | 22 (10.8%) | NA | NA | NA | NA | NA |
| Fan et al.65 | Shanghai, China | 148 | 27 (18.2%) | 32 (21.6%) | 26 (17.6%) | 6 (4.1%) | NA | NA | 9 (6.1%) |
| Qian et al.72 | Shanghai, China | 324 | 51 (15.7%) | 53 (16.4%) | NA | 4 (1.2%) | NA | 136 (42%) | 21 (6.5%) |
| Wu et al.66 | Jiangsu, China | 80 | 3 (3.75%) | 3 (3.75%) | NA | NA | 17 (21.3%) | 2 (2.5%) | 1(1.3%) |
| Yip et al.44 | Hong Kong, China | 1040 | 184 (22.5%) | 184 (22.5%) | NA | NA | NA | NA | NA |
| Sun et al.73 | Nanyang, China | 150 | 24 (16%) | 15 (10%) | NA | NA | 47 (31%) | NA | 3 (2%) |
| Wu et al.56 | Wuhan, China | 157 | 12 (7.6%) | 25 (16.9%) | NA | NA | 32 (21.6%) | NA | NA |
| Du et al.60 | Wuhan, China | 85 | 14 (16.5%) | 28 (32.9%) | NA | NA | 70 (82.4%) | 67 (78.8%) | 30 (35.3%) |
| Guan et al.74 | 30 provinces, China | 1099 | 158 (21.3%) | 168(22.2%) | NA | NA | 277 (41.0%) | NA | 76 (10.5%) |
| Cai et al.50 | Shenzhen, China | 298 | 39 (13.1%) | 25 (8.4%) | 51 (17.1%) | 1 (0.3%) | 23 (8.4%) | NA | 24 (8.1%) |
| Zhang et al.55 | Wuhan, China | 95 | 52 (54.7%) | 45 (47.4%) | NA | NA | 74(77.9%) | NA | NA |
| Richardson et al.49 | New York, USA | 5700 | 2176 (39.0%) | 3263 (58.4%) | NA | NA | NA | NA | NA |
NA not available, ALT, alanine aminotransferase; AST, aspartate transaminase; GGT, gamma-glutamyltransferase; ALP, alkaline phosphatase; LDH, lactate dehydrogenase; ALB, albumin; TBIL, total bilirubin abnormal.