Table 1.
Hydrogel coatings for active agents release in biomedical area to create Ti active surfaces.
| Hydrogel Coating | Released Active Agent (s) | Biomedical Application | Reference |
|---|---|---|---|
| Polycarboxylic/amino functionalized hyaluronic acid | Vancomycin | Prevention of bacterial adhesion | [154] |
| Hyaluronic acid | Vancomycin | Enhancement of osseointegration | [155] |
| Recombinant human bone morphogenetic protein (rhBMG)-2 | Enhancement of peri-implant osteogenesis | [156] | |
| Hyaluronic acid and polylactic acid | Vancomycin Gentamicin Amikacin Tobramycin N-acetylcysteine Sodium salicylate |
Enhancement of antibacterial properties | [157] |
| Vancomycin Tobramycin |
Enhancement of antibacterial properties | [158] | |
| Carboxymethyl chitosan | Silver nanoparticles | Improve antibacterial and bioactive properties | [159] |
| Carboxymethyl chitosan and chitosan | Interleukin-4 (IL-4) and interferon-γ (IFN-γ) cytokines | Immunomodulation and anti-inflammatory properties | [160] |
| Chitosan | Vancomycin | Bone regeneration | [161] |
| Ibuprofen | Drug elution on conductive implants | [162] | |
| Ibuprofen | Controlled drug delivery system | [163] | |
| Interleukin-4 (IL-4) and heparin | Anti-inflammatory, anti-coagulation and anti-thrombus | [164] | |
| Silver nanoparticles and naproxen | Enhancement of antibacterial and anti-inflammatory properties | [165] | |
| Chitosan and silica xerogel | Fibroblast growth factor | Bioactivity enhancement | [166] |
| Chitosan and gelatin | Ampicillin | Tissue engineering | [167] |
| Gelatin | Antimicrobial peptide (AMP) and silicate nanoparticles | Prevention of infections and promotion of bone formation | [168] |
| Gelatin and alginate | Vancomycin Gentamicin |
Reduction of implant-related infection | [169] |
| Alginate | Dopamine | Regulation of osteoclastic and osteogenic responses | [170] |
| Alginate and 4-vynilphenylboronic acid | Vascular endothelial growth factor (VEGF) | Local drug delivery system | [171] |
| Starch | Vancomycin | Prevention of bone infections | [172] |
| Polyvinyl alcohol (PVA) and phospholipid polymer (PMBV) | Paclitaxel | Anticancer therapy | [173] |
| poly(2-hydroxyethyl methacrylate) | Ciprofloxacin | Prevent implant associated infections | [174] |
| poly(ethylene–glycol diacrylate) and acrylic acid | Silver nanoparticles | Enhancement of antibacterial properties | [175] |