Fig. 6.

Effect of 7-chloro-4-(phenylselanyl) quinoline (4-PSQ) or paroxetine or donepezil on the activity of antioxidant enzymes in mice submitted to acute restraint stress (ARS). Superoxide dismutase (SOD) activity in a prefrontal cortex and b hippocampus; Glutathione peroxidase (GPx) activity in c prefrontal cortex and d hippocampus; Glutathione reductase (GR) activity in e prefrontal cortex and f hippocampus. Values are expressed as mean ± standard error of the mean (S.E.M.) (n = 7). (*) denotes p < 0.05, (**) denotes p < 0.01, (***) denotes p < 0.001, and (****) denotes p < 0.0001 when compared to the non-stressed control group. (#) denotes p < 0.05, (##) denotes p < 0.01, (###) denotes p < 0.001, and (####) denotes p < 0.0001 when compared to the ARS-induced group. (&) denotes p < 0.05 and (&&) denotes p < 0.01 when compared to the ARS + 4-PSQ group (one-way ANOVA followed by Tukey’s test)