Table 1.
General baseline parameters of the IMN group and non-IMN group
| General parameter | IMN (n = 374) | Non-IMN (n = 296) | p value |
|---|---|---|---|
| Male sex | 216 (57.8) | 167 (56.4) | 0.729 |
| Age, yr | 48 (36–55)b | 40 (31–51) | < 0.001 |
| WBC, 109/L | 6.00 (5.03–7.30) | 6.20 (5.09–7.57) | 0.546 |
| Hemoglobin, g/L | 140 (126–151)a | 133 (116–152) | 0.005 |
| Platelet, 109/L | 265 (226–305)b | 247 (206–297) | < 0.001 |
| Total protein, g/L | 49.2 (43.1–56.0)b | 64.1 (51.7–70.8) | < 0.001 |
| Albumin, g/L | 25.3 (21.4–29.8)b | 36.0 (24.7–41.1) | < 0.001 |
| Globulin, g/L | 23.87 ± 4.29b | 28.19 ± 4.66 | < 0.001 |
| BUN, mg/dL | 13.2 (10.6–16.5)b | 17.6 (12.9–23.7) | < 0.001 |
| Serum creatinine, mg/dL | 0.71 (0.59–0.84)b | 1.00 (0.74–1.44) | < 0.001 |
| eGFR, ml/min/1.73 m2 | 109 (97–119)b | 88 (54–109) | < 0.001 |
| CysC, mg/L | 0.87 (0.76–1.03)b | 1.24 (0.92–1.75) | < 0.001 |
| Cholesterol, mg/dL | 297.8 (246.6–370.8)b | 223.1 (182.5–300.5) | < 0.001 |
| HDL-C, mg/dL | 56.5 (47.2–69.1)b | 48.3 (39.4–58.4) | < 0.001 |
| LDL-C, mg/dL | 181.9 (146.7–241.2)b | 140.6 (111.9–193.0) | < 0.001 |
| Anti-PLA2R, RU/mL | 66.23 (13.02–173.23)b | < 2c | < 0.001 |
| U-RBC, HPF | 6.7 (2.9–15.5)b | 4.4 (1.5–17.8) | < 0.001 |
| Urinary protein, g/day | 4.51 (2.54–7.55)b | 2.25 (1.07–4.80) | < 0.001 |
Values are presented as number (%), median (interquartile range), or mean ± SD.
IMN, idiopathic membranous nephropathy; WBC, white blood cell; BUN, blood urea nitrogen; eGFR, estimated glomerular filtration rate; CysC, serum cystatin C; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; PLA2R, phospholipase A2 receptor; U-RBC, urinary red blood cell; HPF, high power field.
Compared with the non-IMN group,
a
p < 0.01.
b
p < 0.001.
c
All three quartiles of anti-PLA2R in the non-IMN group were less than 2 RU/mL.