Table 1.
Demographics, history, prior treatment | Symptoms at onset | First symptom until RT-PCR +a | First symptom until RT-PCR–a | Time from first symptom to hospital/ICU admissiona | ICU staya | Hospital staya | Final physical/psychological outcome | |
---|---|---|---|---|---|---|---|---|
Patient 1 | 64 years old, male, 82 kg, 176 cm, high blood pressure, dyslipidaemia, amlodipine, telmisartan, omeprazole | Fever, malaise, muscle aches, headache, diarrhoea, dyspnoea, vomiting, asthenia, dizziness, vertigo | 9 | 30 | 10/10 | 11 | 44 | Microthrombi in pulmonary arteries requiring therapeutic doses of LMWH, weight loss, fatigue/severe malaise, PTDSb |
Patient 2 | 63 years old, male, 65 kg, 172 cm, high blood pressure, dyslipidaemia, asthma, amlodipine, atorvastatin, prednisone, budesonide, formoterol | Fever, dry cough, asthenia, fatigue, dyspnoea, palpitations, dizziness, vertigo | 7 | 23 | 9/11 | 17 | 30 | Weight loss, palpitations, fatigue, insomnia/severe malaise, PTDSb |
Quetiapine | ||||||||
Patient 3 | 61 years old, female, 65 kg, 158 cm, osteoporosis, vitamin D | Fever, malaise, headache, diarrhoea, nausea, mild dizziness (all of short duration), anosmia, ageusia | 5 | 20 | NA | 23 | NA | No sequelae |
Patient 4 | 57 years old, female, 70 kg, 160 cm, occasional smoker, hypothyroidism, levothyroxine | Fever, anosmia, ageusia | NA | NA | NA | 36 | NA | No sequelae |
Patient 5 | 63 years old, male, 90 kg, 160 cm, high blood pressure, losartan, atorvastatin | Cough, fever, malaise | 10 | 23 | 10/10 | 61 | NA | Tracheostomy, bilateral pneumothorax, thoracotomy, death |
Patient 6 | 74 years old, male, high blood pressure., pulmonary embolism, dyslipidaemia, candesartan, hydrochlorothiazide, allopurinol | Cough, fever, dizziness, myalgia | 7 | NAc | 7/10 | 60 | NA | Tracheostomy, death |
Patients 1 and 3 and patients 2 and 4 were couples, patients 5 and 6 died in the ICU.
LMWH: low molecular weight heparin; NA: not applicable; PTDS: post-traumatic distress syndrome; RT-PCR: reverse transcriptase-polymerase chain reaction.
In days.
See text for additional explanation.
Remained positive until death.