Figure 6. Radiotherapy port-associated annular and targetoid erythema on the left chest and annular erythema on the right breast are the presenting manifestations of cutaneous metastases in a woman with invasive ductal left breast carcinoma.

Distant (A and B) and closer (C and D) lateral view of the right breast (A and C) and frontal view of the left chest (B and D) of a woman with invasive ductal carcinoma of the left breast who has developed breast cancer cutaneous metastases not only within the radiation therapy port (black rectangle) on her left chest but also on her right breast. The red cutaneous metastases appeared as annular (black ovals) and targetoid (black arrow) macules which the patient initially considered to be dermatitis. The targetoid lesion was flat and appeared as a red ring surrounding the white central area. Right breast and left chest skin biopsies of the erythematous patches both showed metastatic carcinoma (compatible with the patient’s primary breast cancer) in the dermis and within the vascular spaces.