Table 1. Baseline demographics of patients in the training cohort.
| Characteristics | Total patients | No late recurrence, n (%) | Late recurrence, n (%) | P value |
|---|---|---|---|---|
| N | 302 | 227 (75.2) | 75 (24.8) | |
| aMAP score | <0.001 | |||
| ≤63.8 | 204 | 181 (79.7) | 23 (30.7) | |
| 63.9–67.8 | 61 | 43 (18.9) | 18 (24.0) | |
| >67.8 | 37 | 3 (1.3) | 34 (45.3) | |
| Age (years) | 0.091 | |||
| ≤60 | 195 | 140 (61.7) | 55 (73.3) | |
| >60 | 107 | 87 (38.3) | 20 (26.7) | |
| Gender | <0.001 | |||
| Female | 70 | 66 (29.1) | 4 (5.3) | |
| Male | 232 | 161 (70.9) | 71 (94.7) | |
| Max size (cm) | 1.000 | |||
| ≤2.2 | 171 | 98 (43.2) | 33 (44.0) | |
| >2.2 | 129 (56.8) | 42 (56.0) | ||
| Tumor number | <0.001 | |||
| One | 224 | 193 (85.0) | 31 (41.3) | |
| Multiple | 78 | 34 (15.0) | 44 (58.7) | |
| Antiviral therapy | 0.084 | |||
| No | 149 | 105 (46.3) | 44 (58.7) | |
| Yes | 153 | 122 (53.7) | 31 (41.3) | |
| HBeAg | 0.315 | |||
| Positive | 217 | 167 (73.6) | 50 (66.7) | |
| Negative | 85 | 60 (26.4) | 25 (33.3) | |
| Preoperative HBV-DNA load >104 copies/mL | <0.001 | |||
| Yes | 44 | 12 (5.3) | 32 (42.7) | |
| No | 258 | 215 (94.7) | 43 (57.3) | |
| HBsAg (U/mL) | 0.194 | |||
| ≤250 | 194 | 151 (66.5) | 43 (57.3) | |
| >250 | 108 | 76 (33.5) | 32 (42.7) | |
| Cirrhosis | 0.389 | |||
| No | 83 | 59 (26.0) | 24 (32) | |
| Yes | 219 | 168 (74.0) | 51 (68.0) | |
| Child–Pugh class | ||||
| A | 293 | 219 (96.5) | 74 (98.7) | 0.565 |
| B | 9 | 8 (3.5) | 1 (1.3) | |
| ALBI grade | 0.837 | |||
| 1 | 164 | 122 (53.7) | 42 (56.0) | |
| 2 | 138 | 105 (46.3) | 33 (44.0) | |
| AFP (ng/mL) | 0.362 | |||
| ≤400 | 267 | 198 (87.2) | 69 (92.0) | |
| >400 | 35 | 29 (12.8) | 6 (8.0) | |
| AST (U/L) | 0.742 | |||
| ≤40 | 252 | 188 (82.8) | 64 (85.3) | |
| >40 | 50 | 39 (17.2) | 11 (14.7) | |
| ALT (U/L) | 0.908 | |||
| ≤40 | 65 | 48 (21.1) | 17 (22.7) | |
| >40 | 237 | 179 (78.9) | 58 (77.3) | |
| PLT (109/L) | 0.112 | |||
| ≤100 | 104 | 72 (31.7) | 32 (42.7) | |
| >100 | 198 | 155 (68.3) | 43 (57.3) | |
| TBIL (μmol/L) | 0.295 | |||
| ≤17.1 | 206 | 159 (70.0) | 47 (62.7) | |
| >17.1 | 96 | 68 (30.0) | 28 (37.3) | |
| γ-GT (U/L) | 0.279 | |||
| ≤60 | 218 | 168 (74.0) | 50 (66.7) | |
| >60 | 84 | 59 (26.0) | 25 (33.3) | |
aMAP, age-male-albumin-bilirubin-platelet; ALBI, albumin-bilirubin; AFP, alpha-fetoprotein; AST, aspartic transaminase; ALT, alanine transaminase; PLT, platelet; TBIL, total bilirubin; γ-GT, gamma-glutamyltransferase.