Table 3. The kinase, miRNA and transcription factor-target networks of EIF2S2 in HCC (LinkedOmics).
| Enriched category | Geneset | LeadingEdgeNum | P value | FDR |
|---|---|---|---|---|
| Kinase target | Kinase_MAPK1 | 54 | 0 | 0.31931 |
| Kinase_MAP3K6 | 1 | 0.0042918 | 0.30758 | |
| Kinase_DYRK1A | 7 | 0.0043668 | 0.35358 | |
| Kinase_CSNK2A1 | 84 | 0.0068493 | 0.63526 | |
| Kinase_PIM1 | 8 | 0.011765 | 0.29544 | |
| miRNA target | ATACTGT, MIR-144 | 59 | 0 | 0 |
| TAGGTCA, MIR-192, MIR-215 | 17 | 0 | 0 | |
| TGTTTAC, MIR-30A-5P, MIR-30C, MIR-30D, MIR-30B, MIR-30E-5P | 184 | 0 | 0 | |
| TACTTGA, MIR-26A, MIR-26B | 82 | 0 | 0 | |
| GCTTGAA, MIR-498 | 33 | 0 | 0 | |
| Transcription factor target | GGAANCGGAANY_UNKNOWN | 38 | 0 | 0 |
| V$FREAC2_01 | 60 | 0 | 0 | |
| YNGTTNNNATT_UNKNOWN | 79 | 0 | 0 | |
| V$FREAC4_01 | 42 | 0 | 0.000724 | |
| V$FOXO4_02 | 75 | 0 | 0.000905 |
V$, the annotation found in Molecular Signatures; Database (MSigDB) for transcription factors (TF). EIF2S2, eukaryotic translation initiation factor 2 subunit beta; HCC, hepatocellular carcinoma; LeadingEdgeNum, the number of leading edge genes; FDR, false discovery rate from Benjamini and Hochberg from gene set enrichment analysis (GSEA).