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. 2021 Dec;12(6):2919–2929. doi: 10.21037/jgo-21-774

Table 3. Meta-analysis results of tumor marker indicators.

Factors Number of participating patients Number of
literatures
Statistical method I2C with P value Effect estimate P value
CEA 242 2 MD (IV, fixed, 95% CI) 0% with 0.86 −14.26 (−14.81, −13.71) <0.00001
CA199 242 2 MD (IV, fixed, 95% CI) 19% with 0.27 −138.87 (−143.21, −132.52) <0.00001

CEA, carcinoembryonic antigen; CA199, carbohydrate antigen 19-9; MD, mean difference; 95% CI, 95% confidence interval.