Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic diagram of related mechanism of CUR. Note: CUR up-regulates the level of BDNF by up-regulating JMJD3 and suppressing the level of H3K27me3 in the BDNF promoter region, thereby reducing the level of Aβ and improving MSR. In short, CUR exerts its anti-AD effect by regulating the JMJD3-H3K27me3-BDNF axis.
