Table 3.

Percentage reduction of tumor weight at autopsy in the high dose treatment groups

Treatment group	Percentage reduction of tumor weight	P-value
Control
Brom (6.0 mg/kg) + Ac (500 mg/kg)	38.53±10.21	0.0048
GEM (5.0 mg/kg)	61.39±13.69	0.0006
GEM (5.0 mg/kg) + Brom (3.0 mg/kg) + Ac (300 mg/kg)	59.57±27.43	0.0225
GEM (2.0 mg/kg) + Brom (6.0 mg/kg) + Ac (500 mg/kg)	38.94±11.11	0.0060
GEM (5.0 mg/kg) + Brom (6.0 mg/kg) + Ac (500 mg/kg)	53.80±10.52	0.0020

Percentage reduction of tumor weight = [tumor weight (control) - tumor weight (treatment)/tumor weight (control)] ×100. Data are presented as mean ± SD; P-values were obtained through t-test; significance level: P<0.05.