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Flow diagrams of the study. A. Scheme of the study periods. B. Scheme of the study subjects. *At the beginning of the experiment, 2 subjects in the 0.15 mg/kg group and 4 subjects in the 0.4 mg/kg group received ciprofol by infusion pump, but the subsequent administrations were changed to manual injections, which were completed within 1 min. Subjects administered medication with an infusion pump were excluded from the PK and PD analyses.
