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. 2021 Dec 15;13(12):14141–14148.

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AUC of the four methods. Note: The abscissa from left to right were HE4+CA125+ROMA, ROMA, HE4, and CA125 diagnostic methods. The ordinate represented the AUC of each diagnostic mode. The AUCs of HE4+CA125+ROMA, ROMA, HE4, and CA125 were 0.966, 0.743, 0.862 and 0.606 respectively. a represents the comparison between HE4+CA125+ROMA and ROMA, χ²=20.00, P<0.001; b represents the comparison between HE4+CA125+ROMA and HE4, χ²=6.88, P=0.09; c represents the comparison between HE4+CA125+ROMA and CA125, χ²=38.52, P<0.001; d represents the comparison between ROMA and HE4, χ²=4.47, P=0.04; e represents the comparison between ROMA and CA125, χ²=4.27, P=0.04; f represents the comparison between HE4 and CA125, χ²=16.78, P<0.001.