Table 1.
Group | Number | Survived | EAE incidence# | Mean day of onset* | Total EAE scores+ | Maximum clinical score on any given day |
---|---|---|---|---|---|---|
Vehicle | 24 | 18 | 17 | 15.4 | 31.2 | 7 |
T3 | 24 | 22 | 14 | 15.8 | 19.0 | 7 |
Sobetirome | 16 | 16 | 11 | 18.1 | 10.8 | 6 |
Sob AM2 | 24 | 24 | 10 | 18.7 | 4.3 | 5 |
only those mice who showed disease were included in mean day onset
treatment was started before onset of disease so treatment is delaying and blocking disease
ANOVA significant p<0.0001