FIGURE 2.

MLST8 is a potential biomarker for ccRCC according to TCGA. A, Expression level of MLST8 in ccRCC was elevated in tumor tissue compared to normal tissue. B, Expression of MLST8 was elevated gradually as ccRCC progressed to stage II and stage III. C, Expression of MLST8 presented as more upregulated in stages T2 and T3 compared to T1. D, Expression of MLST8 in ccRCC patients with stage M1 was remarkedly increased compared that in stage M0. E, There was no significant difference of MLST8 expression between stages N1 and N0 in ccRCC patients. F, OS curve of ccRCC patients based on MLST8 expression (P = .0248)