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MLST8 is an important mediator of FBXW7 inactivation‐induced cell proliferation, migration, and invasion in vitro. A and B, Western blot and CCK8 cell proliferation assay of parental or FBXW7 and/or MLST8 knockout 786‐O and A498 cells. The standard deviation (SD) of at least three independent experiments is shown to indicate statistical significance. C and D, Cell migration and invasion assays of parental or FBXW7 and/or MLST8 knockout 786‐O and A498 cells. *P < .05
