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Association between 14q deletion and downregulated gene expression. The gene expression ratios of (A) HIF1A and (B) L2HGDH were significantly associated with 14q loss (HIF1A; *P = .0253, L2HGDH; **P = .0117, chi‐squared test). In contrast, (C) the gene expression ratios of KLHL33 did not show a significant association with 14q loss (P = .0536). The number of ccRCCs with and without this loss analyzed was 22 and 23, respectively. Gene expression ratios were normalized to GAPDH
