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miR‐16‐5p inhibits malignancy of OS in vitro. A, The expression level of miR‐16‐5p was confirmed by qRT‐PCR in OS cells and tissues. B and C, CCK8 and EdU assays showed that proliferation viability was inhibited by mimic in both OS cells. D and E, Wound‐healing and transwell assays indicated that migration and invasion abilities were suppressed in vitro. F, Colony formation results showed that proliferation ability was suppressed. Data are shown as mean ± SD. *P < 0.05, **P < 0.01
