TABLE 4.

Comparison of urinary metabolite concentrations between clear cell renal cell carcinoma (ccRCC) patients with and without recurrence

Variable	ccRCC without recurrence			ccRCC with recurrence
	Mean concentration preoperation	Mean concentration postoperation	Mean ratio, post / pre	Mean concentration preoperation	Mean concentration postoperation	Mean ratio. post / pre	P value of mean ratio
Urinary metabolite	μmol/L/u‐Cre (mmol/L)	μmol/L/u‐Cre (mmol/L)		μmol/L/u‐Cre (mmol/L)	μmol/L/u‐Cre (mmol/L)
Galactose	0.58	0.0060	1.59	0.53	0.079	7.28	.85
F6P	3.75	0.68	0.20	0.30	8.27	156.57	.20
DS7P	122.24	15.12	6.11	3.47	966.77	19 407.3	.35
Lactic acid	593.11	22.28	0.91	43.11	132.69	38.1	.21
Succinic acid	36.7	0.89	0.036	15.4	6.1	6.74	.13
Glutamine	585.97	101.97	32.7	173.88	367.42	3.65	.95
Glutamic acid	115.4	6.44	2.64	1.76	11.89	39.3	.021
2‐HG	1027.58	4.92	0.11	372.44	72.34	0.37	.025
Glycine	15.62	0.0085	0.58	0.034	0.048	3.38	.047
Kynurenic acid	0.21	0.28	27.89	0.16	0.45	267.0	.11

Abbreviations: 2‐HG, 2‐hydroxyglutarate; DS7P, d‐sedoheptulose 7‐phosphate; F6P, fructose 6‐phosphate.