TABLE 2.

Tumor mutational burden (mutations/Mb)

Case no.	Primary tumor	Liver metastasis
1	23.66	3.38
2	10.1	6.73
3	13.47	10.14
4	5.91	4.24
5	12.73	16.46
6	5.05	5.09
7	2.53	1.69
8	4.23	5.08
9	61.97	5.08
10	6.81	25.76
11	6.81	5.08
12	6.79	7.63
13	6.87	9.04
14	7.72	11.1
15	8.55	8.47
16	11.11	4.29
17	3.40	7.62
18	9.32	9.37
19	8.51	6.77
20	14.46	17.8
21	4.28	4.21
22	10.23	7.60
23	9.35	5.91
24	8.48	6.75
Ave.	10.93	8.14

Case numbers in bold indicate cases in which the TMB status differs between the primary lesion and the liver metastatic lesion.