TABLE 3.

A, Cases with TMB high in the primary lesion. B, Cases with TMB high in the liver metastatic lesion

A	TMB				Clinicopathological features
	Case no.	Primary tumor	Liver metastasis	Ratio	Liver metastasis	Stage	Prognosis	Recurrence (after first liver resection)
1	1	23.66	3.38	7.00	Synchronous	IVA	Dead	+
2	2	10.1	6.73	1.50	Synchronous	IVA	Dead	+
3	9	61.97	5.08	12.20	Metachronous	IIB	Alive	−
4	16	11.11	4.29	2.59	Synchronous	IVA	Alive	−
5	22	10.23	7.60	1.35	Synchronous	IVA	Alive	−
ave.		23.41	5.42	4.93

B	TMB				Clinicopathological features
	Case no.	Primary tumor	Liver metastasis	Ratio	Liver metastasis	Stage	Prognosis	Recurrence (after first liver resection)
1	10	6.81	25.76	0.26	Synchronous	IVA	Alive	+
2	14	7.72	11.1	0.70	Metachronous	IIA	Alive	−
ave.		7.27	18.43	0.48