UMIN000018952.

Study name	Effect of calcium combination lemon drink absorption on lifestyle‐related disease
Methods	Randomised controlled trial
Participants	Healthy women
Interventions	Calcium combination lemon drink, period: 11 months, volume: 30 mL of lemon fruit juice and calcium 35 mg per bottle, frequency: 1 bottle/day Lemon drink, period: 11 months, volume: 30 mL of lemon fruit juice per bottle, frequency: 1 bottle/day No drink
Outcomes	1. Subjective‐objective symptoms by a questionnaire 2. Somatometry 3. Blood pressure 4. Bone mineral density 5. Bone metabolism marker 6. Oxidation stress marker
Starting date	12/10/2015
Contact information	Toshihide Harada, 1‐1 gakuen‐machi Mihara, Hiroshima, Japan
Notes

^{ALP:alkaline phosphatase
ALT: amino transferase
Angpt14: angiopoietin‐like protein 4
BMI: Body Mass Index
CBC: Complete blood count
CO2: carbon dioxide
DBP: Dyastilic blood pressure
ECG:electrocardiogram
FBG: Fasting blood glucose
GXT: graded exercise test 
HDL: High densituy lipoprotein
HR: Heart rate
IGF‐1: insulin‐like growth factor
LDL: Low density lopoprotein
MCH: mean corpuscular haemoglobin 
MCHC: mean corpuscular haemoglobin concentration
MCV: mean corpuscular volume
MPV: mean platelet volume
PTH: parathyroideahormone
RBC:  blood cell count
RDW: red cell distribution width 
REE: resting energy expenditure
RER: respiratory exchange ratio
RMR: Resting Metabolic rate
SBP: Systolic blood pressure
TC: Total Colesterol
TG: Triglycerides
WBC: white blood cell}