Table 1.

Advantages and disadvantages of different nanopolymers

S. No.	Polymer	Advantages	Disadvantages	References
1	PLGA	Biocompatible, non-toxic polymer and has sustained release properties	Hydrophobicity	(Taghipour-Sabzevar et al. 2019)
2	PCL	Biodegradable, suitable for long term drug delivery system	Takes longer time to degrade in human body	(Aramudan and Senthil 2016)
3	PLA	Non-toxic, biodegradable,	Poor hydrophobicity	(Liu et al. 2020)
4	PEG	Hydrophobic, high drug loading capacity	Sometimes triggers immune response	(Taghipour-Sabzevar et al. 2019)
5	PPE	Faster degradation rate, best for nucleic acid delivery	Causes difficulty in synthesis	(Kamaly et al. 2016)
6	PEA	Biodegradable, hydrophobic due to presence of hydrophobic amino acids	Alteration of amide and ester bond leads to slow degradation	(Kamaly et al. 2016)
7	PPO	Biodegradable, biocompatible	Large scale production is difficult	(Kamaly et al. 2016)
8	PGA	High crystallinity	Poor solubility	(Rezvantalab et al. 2018)