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. 2022 Jan 10;8:17. doi: 10.1038/s41420-021-00794-5

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A Heat map of NPC-related miRNA microarray data (The ordinate showed the name of miRNAs, the tree on the left showed the expression clustering, and the histogram on the upper right showed the color scale). B The remarkably downregulated miRNA intersected with the highly expressed miRNA in peripheral blood EVs from the EVs-miRNA database. C Differential expression of miR-142-5p in expression dataset GSE32960 (The abscissa represented the sample type, the ordinate represented the expression value, and the upper right was the corrected difference p-value).