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. 2022 Jan 10;13:124. doi: 10.1038/s41467-021-27765-9

Fig. 3. Results for the Phase I obtained in lab 1. Individual samples are colored according to tumor (T) stage: T1 - yellow, T2 - orange, T3 - red, T4 - rose, and Tx - brown (information about the stage is not available).

Fig. 3

OPLS-DA for males measured a with UHPSFC/MS and c with shotgun MS for the training set (104 T + 30 N). OPLS-DA for females measured with b UHPSFC/MS and d shotgun MS for the training set (157 T + 49 N). ROC curves for males (M) and females (F) in training (Tr.) and validation (Va.) sets: e UHPSFC/MS, and f shotgun MS. Box plots for molar concentration in human serum from PDAC patients (T) and healthy controls (N) for males (M) and females (F): g SM 41:1 measured by UHPSFC/MS, h SM 41:1 measured by shotgun MS (LR), for both box plots for males (104 T and 30 N) and females (109 T and 49 N), i SHexCer 41:1(OH) measured by MALDI-MS, and j SHexCer 40:1(OH) measured by MALDI-MS, for both box plots for males (15 T and 14 N) and females (18 T and 19 N). In each box plot, the centerline represents the median, the bounds represent the 1st and 3rd quartile and whiskers span 1.5 fold inter-quartile range from the median. Source data are provided as a Source Data file.