Fig. 6. Results for the lipidomic profiling of female serum samples from PDAC patients (T) and healthy controls (N) in Phase III.

a PCA for the training set (211 T + 124 N). b OPLS-DA for the training set (211 T + 124 N). Individual samples are colored according to their tumor (T) stage: T1 - yellow, T2 - orange, T3 - red, T4 - rose, and Tx - brown (information about the stage is not available). c Sensitivity (red), specificity (blue), and accuracy (green) for training and validation sets. d S-plot for the training set with the annotation of most upregulated (red) and downregulated (blue) lipid species. e Heat map for both training and validation sets (271 T + 134 N) using the lipid species concentrations [nmol/mL]. Source data are provided as a Source Data file.