Fig. 4. Evolution of mortality across time, by drug classes.

Mortality associated with myocarditis cases, by drug class (A) and mortality by quartile of time, for each drug class (B–F). Intergroup comparisons assessed by χ² test were performed to assess mortality differences over time, for which results are as follow: A p = 2.1e–90 (significant), B p = 2.8e–05 (significant), C p = 0.2 (not significant), D p = 0.018 (significant), E p = 0.003 (significant), and F p = 5.2e–08 (significant).